Neville leads the all-time series with West Monroe 39-13-2, but the Rebels have won eight regular season meetings in a row and a jamboree thriller a month ago, 7-6.
Neville (3-1) and West Monroe (4-0) have won a combined 20 LHSAA football state championships.
While Neville started the season with a 41-7 loss to another Rebel rival, Ruston, the Tigers have now won three straight games and have gotten things on track, especially defensively.
Led by safety Andrew Cagle, the Neville defense has given up just 32 points in the last three games combined (vs. Warren Central, Ouachita and Carroll).
Neville has found a strong run game as of late.
Quarterback Jordan Thomas has rushed for over 500 yards in 4 games this season.
The game figures to be a hard-nosed, smash-mouth contest as both offenses look to use a powerful running game to control the clock and wear down the defense.'
West Monroe quarterback Garrett Kahmann and running back Cam Wright have combined for over 700 yards through four games rushing and the emergence of fullback Cayden Pierce and running back Charlie Norman give the Rebels plenty of weapons to run the football.
If special teams come into play late in the game, returner Michael Hamburg (3 TDs) and Zach Murphy along with kicker Reece Aultman (perfect on PAT kicks) along with punter Peyton Todd have had strong starts to the 2018 campaign.
The game will stream live on wmhs.tv and on the radio KLIP 105.3 FM. Kickoff is set for 7 p.m.